- The choice
- Serum to Mia or to Zoe, at the boathouse, after the fight with mutated Jack.
- When
- About two thirds of the way in. The ending itself comes much later.
- Trophies
- End of the Night for Mia (Ending 1), Just A Memory Now for Zoe (Ending 2).
The choice
What each choice changes
| Serum to Mia (Ending 1) | Serum to Zoe (Ending 2) | |
|---|---|---|
| Who leaves with Ethan | Mia | Zoe |
| On the way to the wrecked ship | One guide says Zoe stays behind. | One guide says Eveline kills Zoe as you reach the ship. |
| When you find Ethan on the ship | Mia resists Eveline and shoves Ethan to safety. | Mia cannot resist and attacks. You fight her with a crowbar and kill her. |
| The helicopter at the end (one guide) | Mia is with Ethan. | Ethan is alone. |
| Trophy | End of the Night | Just A Memory Now |
Getting both
- Either order works. One trophy guide says neither choice changes much in how the game plays.
- You play as Mia on the wrecked ship in both endings, so the videotape sections and their trophies are the same.
- One trophy guide suggests taking the other ending on the speedrun, so that Madhouse can be played with Mia saved, which skips the extra fight on the ship.
- If you keep a manual save from just before the choice, you can load it after the credits and play from there to the other ending.
- One guide says both endings close with the Baker family photo in the credits and, after the fade to black, a phone vibrating.